Personalized Medicine & Applied Engineering
专业详情
The M.S. degree in Personalized Medicine & Applied Engineering is intended to provide medical students, biomedical, mechanical, and electrical engineers, and computer science majors with the tools to develop innovative 3D solutions for personalized medicine.
Students will learn how to develop and apply 3D technology to address surgical and medical conditions with the goal of personalizing health care treatments to improve clinical outcomes. Courses are taught by both clinical and ladder faculty from Yale School of Medicine and Yale School of Engineering & Applied Science.
Using high-resolution medical imaging; 3D printing; robotics; computer navigation; and extended, virtual, and augmented reality, students will learn to develop truly custom treatments, patient-specific instruments for surgery, and personalized medical devices.
Graduates of the program will be well-positioned to:
- Become leaders in clinical research disciplines focusing on personalized medical treatments, radiological services, identification of pathology, point of care printing services, surgical planning.
- Develop medical education tools.
- Become strong candidates for engineering positions that focus on the development of personalized treatments, the design of custom 3D surgical instruments and guides, custom implant design, tissue engineering, and manufacturing.
For questions and further information, contact Drs. Daniel Wiznia and Steven Tommasini.
Curriculum:
The program is 1 full year: Summer (8 weeks) + 1 academic year (Fall and Spring)
Course Requirements: Given that the Master’s program will attract students from many different backgrounds, students will be granted flexibility in terms of elective course requirements, by being able to select the focus of their special investigation projects as well as an optional biomedical engineering industry collaboration project (“internal internship”). For example, students with a strong engineering background may want to focus on medical school focused classes, while medical students may want to focus on engineering related courses. In order to graduate, students will need to take a total of 8 courses, of which 6 courses are required and 2 of the courses can be chosen from Yale-wide technical electives approved by the DGS.
The following six courses are required of all master’s students:
- ENAS 526a: Clinical Knowledge for an Engineer (summer) An 8-week summer clinical immersion session provides students with early hands-on learning and shadowing of the current 3D innovation landscape. Students will be assigned to a clinical mentor. They will shadow their mentor in the clinics and operating rooms, observing how they incorporate personalized medicine into the treatment of patients.This 8-week clinical immersion program starts in the summer before the academic year. This part of the program provides experience in a clinical environment and gives the student a chance to find a clinical mentor for their thesis research. Students will work with their physician mentors to identify causes of preventable medical/surgical errors, device user-related hazards and device failure hazards, with the goal of addressing these preventable complications with medical device design projects. In addition, students will participate in didactics with a structured summer curriculum focusing on needs identification, assessment and risk management. Participating faculty come from all disciplines.
- ENAS 527a: Personalized Medicine Seminar
- Module 1: Rules and regulations. Basics of medical devices • FDA Regulation, QMS, Design controls • Clinical trials, stats, ethics, IRB, HIPPA
- Module 2: Introduction to image analysis and image processing • Medical imaging, image acquisition, • Image management, PACS, DICOM • Image processing algorithm development
- Module 3: VR/AR/XR • Medical education • Simulation • Diagnostics • Procedures • CCAM • YSM simulation center
- ENAS 528a: Biomedical 3D Printing
- Module 4: 3D Printing • 3D Models • Surgical instruments • Point of care printing • Bioprinting • Quality management, printing validation
- Module 5: Surgical planning • 3D anatomic model creation • Use of CAD with 3D models • Surgical planning tools • Model validation
- Module 6: Image guided intervention • Computer navigation • Robotics • Interventional Medicine
- ENAS 990a and b: Special Investigations; Masters Thesis Research
- ENAS 990a and b: Special Investigations; Masters Thesis Research
- ENAS 529b: Medical Device Design
There is no set list of electives. Electives may be any graduate class offered by the GSAS, School of Management, School of Public Health, School of Medicine, and School of Law as long as they are consistent with the mission of the program (subject to director approval).
Potential electives include, but are not limited to:
ENAS 532a and b: Industry sponsored 3D Design Project – Fall and Spring (Can be taken in place of ENAS 990a and b). Teams of 2-3 students will be paired to work on 3D medical innovation projects with biomedical engineering companies, industry leaders of personalized medicine. This course will serve as a potential “route to employment” by providing students with a year-long internship / “internal interview” with a biomedical technology company’s engineering team. These projects may involve the student developing novel software, hardware, manufacturing validations, medical devices, surgical instruments, or 3D printing modalities
ENAS 531b: Medical Software Design
ENAS 912a: Biomedical Image Processing and Analysis
MGT 992a: Healthcare Strategy
NURS 511a: Clinical Applications of Human Anatomy
ENAS 600a or b: Computer-Aided Engineering
ANAT 100a or b: Human Anatomy and Development
MGT 657b: Creating Healthcare and Life Science Ventures
YSM Investigative Medicine Courses
IMED 625: Principles of Clinical Research
IMED 630: Practical and Ethical Issues in Clinical Investigation
CDE 650e: Introduction to Evidence-Based Health Care & Medicine
IMED 645: Introduction to Biostatistics
Applying:
The application process for 2023-2024 opens on August 15 and the deadline for applications is December 15. Check the Yale Graduate School of Arts and Science website for details.
Tuition is set by the GSAS. There is no financial assistance available for students enrolled in the Master’s degree program. Further, due to the course work, students typically cannot devote sufficient time to be eligible for research funding. However, several of our Master’s students perform a teaching fellowship for undergraduate courses and receive compensation for this work.
